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Department VUmc:Neurology




Name           : Philip Scheltens
Department  : Neurology / Alzheimer Center
Position        : Professor and Director


Dr Philip Scheltens studied at the VU University  Amsterdam, Netherlands, gaining his MD in 1984, and PhD (Magnetic Resonance Imaging in Alzheimer's disease) in 1993. Clinical residencies in neurosurgery at the Municipal Hospital Slotervaart, and at the Vrije Universiteit Medical Centre, Amsterdam, supported his academic development.

Dr Scheltens is Professor of Cognitive Neurology and Director of the Alzheimer Center at the VU University Medical Center in Amsterdam. His main clinical and research interests are Alzheimer's disease, vascular dementia, frontotemporal dementia, magnetic resonance imaging, PET imaging and biomarkers. He is active in the field of biomarkers and clinical trials and has been the national PI for many studies, including fase 1-3 multicenter clinical trials. He founded and directs the Alzheimer Center since 2000, from which over 20 PhD theses have appeared since then.

Dr Scheltens is an active member of several societies including the Dutch Society for Neurology, the International Psychogeriatric Association, the American Academy of Neurology, the Alzheimer Imaging Consortium, the ISTAART consortium  and the European College of Neuropsychopharmacology. He has been instrumental in organising several national and international conferences among which the Imaging symposium attached to ICAD. He chairs the dementia panel of the European Federation of Neurological Societies.

He is associate editor of the Journal of Neurology, Neurosurgery and Psychiatry and book review editor of Alzheimer Disease and Associate Disorders. He is chief editor of the official journal of the Dutch Society of Neurology (Tijdschrift voor Neurologie en Neurochirurgie).
He is also member of the editorial boards of Dementia and Geriatric Cognitive Disorders and International Journal of Geriatric Psychiatry, and acts as an ad hoc reviewer of scientific articles for, amongst others, The Lancet (Neurology); Stroke; Neurology, Annals of Neurology, New England Journal of Medicine, Brain and Science.

He has authored more that 300 peer reviewed papers and > 50 book chapters. Dr Scheltens co-edited the book on Magnetic Resonance in Dementia (Springer) and co-edited the book on Functional Magnetic Resonance Imaging: Clinical Applications (Oxford University Press).. He is Treasurer of the International Society for Vascular Behavioural and Cognitive Disorders (Vas-Cog) since 2003.


Professor Scheltens is director of the Alzheimer center and codirector of the Program Neurodegeneration of the NCA. He supervises alle research within the Alzheimer Center. For specific projects please look at Neurodegeneration program and on www.alzheimercentrum.nl


Sluimer JD, Bouwman FH, Vrenken H, Blankenstein MA, Barkhof F, van der Flier WM, Scheltens P. Whole-brain atrophy rate and CSF biomarker levels in MCI and AD: A longitudinal study. Neurobiol Aging 2008 Aug 7; [Epub ahead of print]

Stam CJ, de Haan W, Daffertshofer A, Jones BF, Manshanden I, van Cappellen van Walsum AM, Montez T, Verbunt JPA, de Munck JC, van Dijk BW, Berendse HW, Scheltens P. Graph theoretical analysis of magnetoencephalographic functional connectivity in Alzheimer's disease. Brain 2009;132:213-224.

Staekenborg SS, van der Flier WM, van Straaten ECW, Lane R, Barkhof F, Scheltens P.  Neurological signs in relation to type of cerebrovascular disease in vascular dementia. Stroke 2008;39:317-322.

Bouwman FH, Schoonenboom SNM, Van der Flier WM,  Van Elk EJ, Kok A, Barkhof F, Blankenstein MA, Scheltens P. CSF biomarkers and medial temporal lobe atrophy predict dementia in mild cognitive impairment. Neurobiol Aging 2007;28:1070-1074.

Bouwman FH, Van der Flier WM, Schoonenboom NSM, Van Elk EJ, Kok A, Rijmen F, Blankenstein MA, Scheltens P. Longitudinal changes of CSF biomarkers in memory clinic patients. Neurology 2007; 69:1006-1011.


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