H.V. Berendse
| Telefoon: | +3120 44 44444 |
| E-mail: | Contact form |
| Department VUmc: | Neurology |
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NAME : Henk W. Berendse, MD PhD
CONTACT
Department : Department of Neurology
Position : Neurologist
CURRICULUM VITAE
Henk Berendse received his MD (with honours) in 1988 at the VU University Medical Centre in Amsterdam. He did his PhD studies in basal ganglia neuroanatomy in the Department of Anatomy of the Vrije Universiteit, Amsterdam, and received his degree (with honours) in 1991. From 1991 to 1992 he worked as a Visiting Scientist at the Department of Neurology (Head: Prof Dr Robert C. Griggs) of the University of Rochester, Rochester NY, USA. Subsequently, from 1992 until 1998 he was trained in Neurology at the VU University Medical Centre in Amsterdam, where he is currently working as a consultant neurologist with a special interest in Movement Disorders. In 2003 he received the Prof Dr Hans Lakke prize for his research on Parkinson’s disease. In 2005 he became Clinical Coordinator of MEG Research at the VU University Medical Centre. Since 2008 he runs the Movement Disorders service at the VU University Medical Centre. He served as Secretary of the Dutch Federation of Neuroscience Organizations (2004-2006). Presently, he is board member of the International Basal Ganglia Society (IBAGS; Secretary from 2004-2007), member of the Research Advisory Panel of the Dutch Parkinson’s Disease Society, and board member of the Nederlandse Werkgroep Bewegingsstoornissen. His current research interests include non-motor disturbances in Parkinson’s disease, in particular olfactory dysfunction and cognitive decline, and the development of early diagnostic procedures and biomarkers of the disease process.
CURRENT PROJECTS
Olfactory dysfunction, cognitive impairments and subtle motor disturbances as potential presymptomatic, diagnostic markers of Parkinson’s disease.
Prevalence and characteristics of olfactory dysfunction in Parkinson’s disease (collaboration with prof.dr. Th. Hummel, Germany; prof.dr. R.L. Doty, USA).
Genomics and proteomics in cerebrospinal fluid, blood, and post-mortem human brain tissue of Parkinson’s disease patients to identify biomarkers related to disease progression (collaboration with dr. W.D.J. van de Berg).
Cognitive dysfunction in Parkinson’s disease: longitudinal assessment using neuropsychological testing, and structural and functional brain imaging.
Functional brain networks in Parkinson’s disease-related dementia.
Modulation of functional brain networks by repetitive transcranial magnetic stimulation to study cortico-cortical and cortico-striatal connectivity in Parkinson’s disease (collaboration dr. Y.D. van der Werf and dr. O van den Heuvel).
Efficiency of physiotherapeutic care in PD: the ParkinsonNet trial (collaboration prof.dr. B. Bloem, UMCN)
Relationship between vitamin D and physical performance in Parkinson’s disease (collaboration prof.dr. P. Lips and dr. EMW Eekhoff)
KEY PUBLICATIONS
Berendse HW, Booij J, Francot CMJE, Bergmans PLM, Hijman R, Stoof JC, Wolters ECh. Subclinical dopaminergic dysfunction in asymptomatic Parkinson’s disease patients’ relatives with a decreased sense of smell. Ann Neurol 50 (2001) 34-41.
Ponsen MM, Stoffers D, Booij J, Van Eck-Smit BLF, Wolters ECh, Berendse HW. Idiopathic hyposmia as a preclinical sign of Parkinson’s disease. Ann Neurol 56 (2004) 173-181.
Stoffers D, Bosboom JLW, Deijen JB, Wolters EC, Berendse HW, Stam CJ. Slowing of oscillatory brain activity is a stable characteristic of Parkinson’s disease without dementia. Brain 130 (2007) 1847-1860.
Verbaan D, Boesveldt S, Van Rooden SM, Visser M, Marinus J, Macedo MG, Fang Y, Heutink P, Berendse HW, Van Hilten JJ Is olfactory impairment in Parkinson´s disease related to phenotypic or genotypic characteristics? Neurology 71 (2008) 1877-1882.
Boesveldt S, Stam CJ, Knol DL, Verbunt JPA, Berendse HW. Advanced time-series analysis of MEG data as a method to explore olfactory function in healthy controls and Parkinson’s disease patient. Hum Brain Mapp (2009) DOI: 10.1002/hbm.20726.
